{"id":117150,"date":"2022-12-02T11:23:05","date_gmt":"2022-12-02T10:23:05","guid":{"rendered":"https:\/\/ziacom.com\/?p=117150"},"modified":"2023-05-19T13:07:26","modified_gmt":"2023-05-19T11:07:26","slug":"osseointegration-branemark","status":"publish","type":"post","link":"https:\/\/ziacom.com\/en\/did-you-know-that\/osseointegration-branemark\/","title":{"rendered":"Osseointegration: discovered by chance"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_raw_js]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[\/vc_raw_js][vc_column_text]<\/p>\n\n<p>[\/vc_column_text]<div class=\"deeper-spacer clearfix\" data-config='{\"desktop\":50,\"mobile\":30,\"smobile\":30}'><\/div>[vc_column_text]<span data-contrast=\"auto\">When <\/span><b><span data-contrast=\"auto\">Per-Ingvar Br\u00e5nemark (1929-2014)<\/span><\/b><span data-contrast=\"auto\"> discovered osseointegration, he was investigating something slightly different: blood microcirculation in the bone marrow.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">For this study, carried out on rabbits, he developed a system consisting of a <\/span><b><span data-contrast=\"auto\">titanium cylinder with a small optical camera<\/span><\/b><span data-contrast=\"auto\"> that, inserted into the rabbit's femur, would help him see the blood circulation in the bone.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">After several months, and once the study was completed, Br\u00e5nemark wanted to retrieve the microcamera for reuse in another project, but when he tried to remove it, he had a surprise: <\/span><b><span data-contrast=\"auto\">he was unable to separate it from the bone because it had attached itself to the bone.<\/span><\/b><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Br\u00e5nemark called this process of integration between titanium and bone \"<\/span><b><span data-contrast=\"auto\">osseointegration<\/span><\/b><span data-contrast=\"auto\">\".<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">So how did he come up with the idea of using titanium for this? <\/span><b><span data-contrast=\"auto\">The choice of material was also a matter of chance<\/span><\/b><span data-contrast=\"auto\">. One of his colleagues at Lund University, Hans Emneus, told him about \"a new material coming from Russia that he was testing in hip prostheses\". It was <\/span><b><span data-contrast=\"auto\">titanium<\/span><\/b><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">However, and as Br\u00e5nemark himself clarified in one of his last interviews, despite the undoubted importance of the material, the real question was \"why the body did not reject it\", and this is where he had a lot to contribute.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">The first fields in which he applied osseointegration after discovering it were orthopaedics and plastic surgery, until he realised <\/span><b><span data-contrast=\"auto\">its potential in oral dentistry <\/span><\/b><span data-contrast=\"auto\">and joint and limb prosthetics.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">After 10 years of animal testing, he finally <\/span><b><span data-contrast=\"auto\">developed a technique that ensured acceptance of the implant by the body<\/span><\/b><span data-contrast=\"auto\">: \"We couldn't just apply it to people; there were already rudimentary implant techniques that didn't work very well, and we didn't want ours to be another failure,\" he said.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<h2><b><span data-contrast=\"auto\">Per-Ingvar Br\u00e5nemark, the father of modern dental dentistry<\/span><\/b><\/h2>\n<p><span data-contrast=\"auto\">Thanks to this discovery, Br\u00e5nemark, who is now known as the <\/span><b><span data-contrast=\"auto\">\u00abfather of modern implant dentistry\u00bb<\/span><\/b><span data-contrast=\"auto\">, received numerous awards, among them:<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559684&quot;:-2,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Swedish Society of Medicine Soederberg Prize.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559684&quot;:-2,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Medal of the Swedish Academy of Engineering for Technical Innovation.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559684&quot;:-2,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" aria-setsize=\"-1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Harvard School of Dental Medicine Distinction.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559684&quot;:-2,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" aria-setsize=\"-1\" data-aria-posinset=\"3\" data-aria-level=\"1\"><span data-contrast=\"auto\">Honorary Fellowship of the Royal Society of Medicine in the United Kingdom.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559684&quot;:-2,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" aria-setsize=\"-1\" data-aria-posinset=\"4\" data-aria-level=\"1\"><span data-contrast=\"auto\">Honorary Doctorate from the Universidad Andr\u00e9s Bello Chile.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559684&quot;:-2,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" aria-setsize=\"-1\" data-aria-posinset=\"5\" data-aria-level=\"1\"><span data-contrast=\"auto\">Doctor Honoris Causa from the European University of Madrid.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559684&quot;:-2,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">European Inventor Award 2011 in recognition of a lifetime of research and clinical work.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><span data-contrast=\"auto\">It has also earned him <\/span><b><span data-contrast=\"auto\">two Nobel Prize nominations<\/span><\/b><span data-contrast=\"auto\">, a nomination for the <\/span><b><span data-contrast=\"auto\">Prince of Asturias Award<\/span><\/b><span data-contrast=\"auto\"> and more than 30 honorary positions throughout Europe and North America.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span>[\/vc_column_text]<div class=\"deeper-spacer clearfix\" data-config='{\"desktop\":50,\"mobile\":30,\"smobile\":30}'><\/div>[vc_column_text]<\/p>\n<h2 style=\"font-size: 18px;\"><i>You may also like<\/i><\/h2>\n<p>[\/vc_column_text]<div class=\"deeper-spacer clearfix\" data-config='{\"desktop\":50,\"mobile\":30,\"smobile\":30}'><\/div>[vc_basic_grid post_type=\"post\" max_items=\"10\" item=\"51432\" grid_id=\"vc_gid:1684494391697-5c578898-e76f-1\" taxonomies=\"2091, 1933\"][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_raw_js]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[\/vc_raw_js][vc_column_text] [\/vc_column_text][vc_column_text]When Per-Ingvar Br\u00e5nemark (1929-2014) discovered osseointegration, he was investigating something slightly different: blood microcirculation in the bone marrow.\u00a0 For this study, carried out on rabbits, he developed a system<\/p>\n","protected":false},"author":1,"featured_media":111841,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1421],"tags":[2094],"class_list":["post-117150","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-did-you-know-that","tag-osseointegration-discovered-by-chance"],"_links":{"self":[{"href":"https:\/\/ziacom.com\/en\/wp-json\/wp\/v2\/posts\/117150","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ziacom.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ziacom.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ziacom.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ziacom.com\/en\/wp-json\/wp\/v2\/comments?post=117150"}],"version-history":[{"count":0,"href":"https:\/\/ziacom.com\/en\/wp-json\/wp\/v2\/posts\/117150\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ziacom.com\/en\/wp-json\/wp\/v2\/media\/111841"}],"wp:attachment":[{"href":"https:\/\/ziacom.com\/en\/wp-json\/wp\/v2\/media?parent=117150"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ziacom.com\/en\/wp-json\/wp\/v2\/categories?post=117150"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ziacom.com\/en\/wp-json\/wp\/v2\/tags?post=117150"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}